Document Detail


Production of interferon and other lymphokines during murine tumour growth. III. Characterization of microbial growth inhibitory activity in cell-free supernatants of rat Zajdela ascites hepatoma.
MedLine Citation:
PMID:  6183957     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A microbial growth inhibitory factor (MGIF) detected in the cell-free fluid of Zajdela ascites hepatoma of the rat was characterized by means of gel filtration, ion exchange chromatography and isoelectric focusing. It was shown that MGIF is a nondialysable protein with a molecular weight of about 19,000 to 25,000. Charge heterogeneity was revealed by isoelectric focusing which demonstrated pI of 3.8--4.5 and 5.0--6.0. MGIF seems to differ from tumour cell-derived MIF detected in the same ascitic fluids.
Authors:
B Fahlbusch; I Schumann; W Zschiesche; L Borecký; V Lackovic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta virologica     Volume:  26     ISSN:  0001-723X     ISO Abbreviation:  Acta Virol.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1983-01-19     Completed Date:  1983-01-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370401     Medline TA:  Acta Virol     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  382-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Ammonium Sulfate / diagnostic use
Animals
Cell-Free System
Interferons / biosynthesis*
Isoelectric Focusing
Liver Neoplasms, Experimental / immunology*,  microbiology
Lymphokines / biosynthesis
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Lymphokines; 7783-20-2/Ammonium Sulfate; 9008-11-1/Interferons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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