Document Detail


Production of chemoenzymatic catalyzed monoepoxide biolubricant: optimization and physicochemical characteristics.
MedLine Citation:
PMID:  22346338     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Linoleic acid (LA) is converted to per-carboxylic acid catalyzed by an immobilized lipase from Candida antarctica (Novozym 435). This per-carboxylic acid is only intermediate and epoxidized itself in good yields and almost without consecutive reactions. Monoepoxide linoleic acid 9(12)-10(13)-monoepoxy 12(9)-octadecanoic acid (MEOA) was optimized using D-optimal design. At optimum conditions, higher yield% (82.14) and medium oxirane oxygen content (OOC) (4.91%) of MEOA were predicted at 15 μL of H(2)O(2), 120 mg of Novozym 435, and 7 h of reaction time. In order to develop better-quality biolubricants, pour point (PP), flash point (FP), viscosity index (VI), and oxidative stability (OT) were determined for LA and MEOA. The results showed that MEOA exhibited good low-temperature behavior with PP of -41(°)C. FP of MEOA increased to 128(°)C comparing with 115(°)C of LA. In a similar fashion, VI for LA was 224 generally several hundred centistokes (cSt) more viscous than MEOA 130.8. The ability of a substance to resist oxidative degradation is another important property for biolubricants. Therefore, LA and MEOA were screened to measure their OT which was observed at 189 and 168(°)C, respectively.
Authors:
Jumat Salimon; Nadia Salih; Bashar Mudhaffar Abdullah
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-01-19
Journal Detail:
Title:  Journal of biomedicine & biotechnology     Volume:  2012     ISSN:  1110-7251     ISO Abbreviation:  J. Biomed. Biotechnol.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-20     Completed Date:  2012-09-07     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101135740     Medline TA:  J Biomed Biotechnol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  693848     Citation Subset:  IM    
Affiliation:
School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, 43600 Selangor, Malaysia. jumat@ukm.my
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Enzymes, Immobilized / metabolism
Ethylene Oxide / analysis
Linoleic Acids / chemical synthesis,  chemistry*,  metabolism
Lipase / metabolism
Lubricants / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Regression Analysis
Spectroscopy, Fourier Transform Infrared
Temperature
Viscosity
Chemical
Reg. No./Substance:
0/Enzymes, Immobilized; 0/Linoleic Acids; 0/Lubricants; 0/monoepoxide linoleic acid; 75-21-8/Ethylene Oxide; EC 3.1.1.-/Novozyme 435; EC 3.1.1.3/Lipase
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