Document Detail


Production, chemical composition and prostaglandin F-2alpha content of uterine fluid in pregnant sheep.
MedLine Citation:
PMID:  966237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A uterine pouch was prepared surgically in ewes before mating to study the production and chemical composition of uterine secretions during pregnancy. Pregnancy was established in 6 sheep and in the first 55 days uterine fluid was present in small amounts (less than 5 ml), whereas between 109 days post coitum and 3 days post partum the volume ranged from 90 to 775 ml. The chemical composition of uterine fluid in pregnancy differed from that of plasma especially in respect of its high concentration of total calcium (up to 83.5 mM) and prostaglandin (PG) F-2a (up to 1500 ng/ml). Progesterone was implicated as an important endocrine factor since uterine fluid (188 ml) with a high concentration of total calcium (53-5 mM) and PGF-2a(235ng/ml) was recovered from a non-pregnant sheep treated with progesterone for 115 days.
Authors:
F A Harrison; R B Heap; N L Poyser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  48     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-01     Completed Date:  1976-12-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  61-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / metabolism
Female
Gestational Age
Potassium / metabolism
Pregnancy
Pregnancy, Animal*
Progesterone / pharmacology
Prostaglandins F / blood,  metabolism*,  secretion
Proteins / metabolism
Sheep / metabolism*
Sodium / metabolism
Uterus / drug effects,  secretion*
Chemical
Reg. No./Substance:
0/Prostaglandins F; 0/Proteins; 57-83-0/Progesterone; 7440-09-7/Potassium; 7440-23-5/Sodium; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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