| Production of c9,t11- and t10,c12-conjugated linoleic acids in humans by Lactobacillus rhamnosus PL60. | |
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MedLine Citation:
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PMID: 20075628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lactobacillus rhamnosus PL60 was tested for whether it can produce c9,t11- and t10,c12-conjugated linoleic acids (CLAs) in human. After consumption of L. rhamnosus PL60, L. rhamnosus was detected in feces 1 week after the start of intake. Analysis by gas chromatography showed that concentrations of c9,t11- and t10,c12-CLAs in serum had increased and concentrations of serum leptin had significantly decreased. Results showed that L. rhamnosus PL60 can survive in human intestines and produce CLAs in human. This is the first report that bacteria can produce CLAs in humans. |
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Authors:
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Kieun Lee; Yeonhee Lee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of microbiology and biotechnology Volume: 19 ISSN: 1017-7825 ISO Abbreviation: J. Microbiol. Biotechnol. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-01-15 Completed Date: 2010-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9431852 Medline TA: J Microbiol Biotechnol Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 1617-9 Citation Subset: IM |
Affiliation:
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Culture Collection of Antimicrobial Resistant Microbes, Department of Biology, Seoul Women's University, Seoul 139-744, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chromatography, Gas DNA, Bacterial / genetics, isolation & purification Drug Administration Schedule Feces / microbiology Female Humans Intestines / metabolism, microbiology Lactobacillus rhamnosus / genetics, growth & development, metabolism* Leptin / blood Linoleic Acids, Conjugated / biosynthesis*, blood, chemistry Male Middle Aged Obesity / metabolism, prevention & control Probiotics / administration & dosage Time Factors |
| Chemical | |
Reg. No./Substance:
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0/DNA, Bacterial; 0/Leptin; 0/Linoleic Acids, Conjugated |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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