Document Detail


Production of branched-chain aroma compounds by Propionibacterium freudenreichii: links with the biosynthesis of membrane fatty acids.
MedLine Citation:
PMID:  18444997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: Short branched-chain fatty acids (BCFAs) are cheese flavour compounds, which result from the conversion of branched-chain amino acids (BCAAs). In Swiss cheese, the production of short BCFAs is mainly performed by Propionibacterium freudenreichii and is strain dependent. Our aim was to investigate the possible links between the biosynthesis of short BCFAs and membrane BCFAs in P. freudenreichii. METHODS AND RESULTS: Short and membrane BCFAs were analysed by gas chromatography-mass spectrometry. Two strains differing in their capacities to release short BCFAs were selected. Tri-deuterated-labelled leucine was used in both strains as a precursor of short extracellular iso-BCFAs and of membrane iso-BCFAs. The proportions of anteiso : iso BCFAs synthesized varied as function of the BCAAs provided in the growth medium, from 72 : 28 to 100 : 0, with leucine and valine, and with isoleucine as sole BC precursors, respectively. The branching pattern of short BCFAs exactly matched that of membrane BCFAs, whatever the exogenous BCAAs provided. CONCLUSIONS: The biosynthesis of short BCFAs is closely related to that of membrane BCFAs in P. freudenreichii. SIGNIFICANCE AND IMPACT OF THE STUDY: The biosynthesis of short BCFAs in P. freudenreichii depends more on the strain than on the presence of exogenous BC precursors.
Authors:
J Dherbécourt; M-B Maillard; D Catheline; A Thierry
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Publication Detail:
Type:  Journal Article     Date:  2008-04-25
Journal Detail:
Title:  Journal of applied microbiology     Volume:  105     ISSN:  1365-2672     ISO Abbreviation:  J. Appl. Microbiol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-06     Completed Date:  2008-12-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706280     Medline TA:  J Appl Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  977-85     Citation Subset:  IM    
Affiliation:
UMR1253 Science et Technologie du Lait et de l'OEuf, INRA, Agrocampus Rennes, Rennes, France.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids, Branched-Chain / analysis,  biosynthesis*
Animals
Bacteriological Techniques
Cell Membrane / metabolism
Cheese / microbiology*
Fatty Acids / analysis,  biosynthesis*
Food Microbiology*
Humans
Leucine / metabolism
Propionibacterium / metabolism*
Chemical
Reg. No./Substance:
0/Amino Acids, Branched-Chain; 0/Fatty Acids; 61-90-5/Leucine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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