Document Detail


Production of HlyA and ClyA haemolysins among quinolone-resistant Escherichia coli isolated from clinical samples.
MedLine Citation:
PMID:  23543875     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Most Escherichia coli resistant to quinolones are not haemolytic. The objective of this study was to determine the phylogroup, clonal relationship, mechanism of quinolone resistance and virulence factors in 70 haemolytic E. coli resistant to nalidixic acid. Sixty-six isolates contained the hlyA gene, belonged to phylogroup B2, and 61 of them presented low-level resistance to fluoroquinolones. Four isolates presented high-level resistance to fluoroquinolones, contained the clyA gene and were included in phylogroup D. One single isolate (phylogroup D, with low level resistance to fluoroquinolones) contained both cytotoxins.
Authors:
Alicia Márquez-López; Belén Ruiz Del Castillo; María Eliecer Cano; Cristina Rodríguez-Mirones; Jesús Oteo; David Sáez; Luis Martínez-Martínez
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-27
Journal Detail:
Title:  SpringerPlus     Volume:  2     ISSN:  2193-1801     ISO Abbreviation:  Springerplus     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-4-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101597967     Medline TA:  Springerplus     Country:  -    
Other Details:
Languages:  ENG     Pagination:  71     Citation Subset:  -    
Affiliation:
Service of Microbiology, University Hospital Marqués de Valdecilla-IFIMAV, Santander, Spain.
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