Document Detail

Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation.
MedLine Citation:
PMID:  20226379     Owner:  NLM     Status:  MEDLINE    
The production of 4-hydroxyphenyllactic acid (4-HO-PLA), a novel antifungal compound, was studied in Lactobacillus sp. SK007 growth. When grown in MRS broth, the strain could produce 75 microg/ml HO-4-PLA, which was the highest reported so far. Tyrosine and 4-hydroxyphenylpyruvic acid (HO-4-PPA) supplements during fermentation could both increase the HO-4-PLA production yield, and the effect of HO-4-PPA on HO-4-PLA production was remarkably better than that of tyrosine. Using HO-4-PPA as substrate could effectively produce HO-4-PLA, which reached 1.26 mg/ml.
Wanmeng Mu; Yu Yang; Jianghua Jia; Tao Zhang; Bo Jiang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-11-22
Journal Detail:
Title:  Journal of bioscience and bioengineering     Volume:  109     ISSN:  1347-4421     ISO Abbreviation:  J. Biosci. Bioeng.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888800     Medline TA:  J Biosci Bioeng     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  369-71     Citation Subset:  IM    
Copyright Information:
Copyright 2009 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, P. R. China.
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MeSH Terms
Antifungal Agents / metabolism*
Food Microbiology
Lactobacillus / drug effects,  growth & development,  metabolism*
Phenylpropionates / metabolism*
Phenylpyruvic Acids / metabolism,  pharmacology
Tyrosine / metabolism,  pharmacology
Reg. No./Substance:
0/Antifungal Agents; 0/Phenylpropionates; 0/Phenylpyruvic Acids; 156-39-8/4-hydroxyphenylpyruvic acid; 306-23-0/4-hydroxyphenyllactic acid; 55520-40-6/Tyrosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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