Document Detail


Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation.
MedLine Citation:
PMID:  20226379     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The production of 4-hydroxyphenyllactic acid (4-HO-PLA), a novel antifungal compound, was studied in Lactobacillus sp. SK007 growth. When grown in MRS broth, the strain could produce 75 microg/ml HO-4-PLA, which was the highest reported so far. Tyrosine and 4-hydroxyphenylpyruvic acid (HO-4-PPA) supplements during fermentation could both increase the HO-4-PLA production yield, and the effect of HO-4-PPA on HO-4-PLA production was remarkably better than that of tyrosine. Using HO-4-PPA as substrate could effectively produce HO-4-PLA, which reached 1.26 mg/ml.
Authors:
Wanmeng Mu; Yu Yang; Jianghua Jia; Tao Zhang; Bo Jiang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-11-22
Journal Detail:
Title:  Journal of bioscience and bioengineering     Volume:  109     ISSN:  1347-4421     ISO Abbreviation:  J. Biosci. Bioeng.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888800     Medline TA:  J Biosci Bioeng     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  369-71     Citation Subset:  IM    
Copyright Information:
Copyright 2009 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
Affiliation:
State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, P. R. China. wmmu@jiangnan.edu.cn
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MeSH Terms
Descriptor/Qualifier:
Antifungal Agents / metabolism*
Fermentation
Food Microbiology
Kinetics
Lactobacillus / drug effects,  growth & development,  metabolism*
Phenylpropionates / metabolism*
Phenylpyruvic Acids / metabolism,  pharmacology
Tyrosine / metabolism,  pharmacology
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Phenylpropionates; 0/Phenylpyruvic Acids; 156-39-8/4-hydroxyphenylpyruvic acid; 306-23-0/4-hydroxyphenyllactic acid; 55520-40-6/Tyrosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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