Document Detail

Prodromal psychosis screening in adolescent psychiatry clinics.
MedLine Citation:
PMID:  21883972     Owner:  NLM     Status:  Publisher    
Background: Research has identified a syndrome conferring ultra-high risk (UHR) for psychosis, although UHR interviews require intensive staff training, time and patient burden. Previously, we developed the Prodromal Questionnaire (PQ) to screen more efficiently for UHR syndromes. Aims: This study examined the concurrent validity of the PQ against UHR status and preliminary predictive validity for later psychotic disorder. Method: We assessed a consecutive patient sample of 408 adolescents who presented to psychiatry clinics in Helsinki, Finland, seeking mental health treatment, including 80 participants who completed the Structured Interview for Prodromal Syndromes (SIPS). Results: A cut-off score of 18 or more positive symptoms on the PQ predicted UHR diagnoses on the SIPS with 82% sensitivity and 49% specificity. Three of 14 (21%) participants with high PQ scores and SIPS UHR diagnoses developed full psychotic disorders within 1 year. Conclusions: Using the PQ and SIPS together can be an efficient two-stage screening process for prodromal psychosis in mental health clinics.
Rachel L Loewy; Sebastian Therman; Marko Manninen; Matti O Huttunen; Tyrone D Cannon
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-31
Journal Detail:
Title:  Early intervention in psychiatry     Volume:  -     ISSN:  1751-7893     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-9-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101320027     Medline TA:  Early Interv Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Blackwell Publishing Asia Pty Ltd.
Department of Psychiatry, University of California, San Francisco Departments of Psychology and Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland.
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