Document Detail

Procutase versus 1% silver sulphadiazine in the treatment of minor burns.
MedLine Citation:
PMID:  20079572     Owner:  NLM     Status:  In-Process    
The purpose of this randomised comparative study was to evaluate the use of silver sulphadiazine (SSD) 1% cream (Group A) with the use of Procutase (Group B) in treating burns with a TBSA <10% and a depth not greater than 2nd degree burns and thus suitable for outpatient management. The two groups were similar in age, gender, race, and extent of burn. Procutase is an ionic hydrogel composed of natural hydrophilic polymers in an active ionic solution with an inhibitor of matrix metalloproteinases MMP-1, -3 and -9 (collagenase/gelatinase). Subjects were seen in follow-up biweekly, and wounds of patients in SSD group were compared with those of Procutase group for healing time, pain score at dressing change, compliance with therapy and complication rate. The result of this study showed that Procutase treated patients had statistically significantly less pain and shorter wound healing time. Procutase can be used successfully in patients with burns that do not require hospital admission.
F R Grippaudo; L Carini; R Baldini
Publication Detail:
Type:  Journal Article     Date:  2010-01-15
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  36     ISSN:  1879-1409     ISO Abbreviation:  Burns     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  871-5     Citation Subset:  IM    
Copyright Information:
2009 Elsevier Ltd and ISBI. All rights reserved.
Plastic Surgery Unit, 2nd Faculty of Medicine, "Sapienza" University of Rome, Rome, Italy.
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