Document Detail


[Processing speed in relapsing-remitting multiple sclerosis: the role played by the depressive symptoms].
MedLine Citation:
PMID:  23143959     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION. Reduced speed of information processing seems to characterize neuropsychological performance in multiple sclerosis (MS) patients. However, the impact in speed of information processing of depressive symptoms, that are highly prevalent in this population, has not been precisely defined yet due to the presence of some methodological limitations in most preceding studies. SUBJECTS AND METHODS. 42 MS remittent recurrent patients, 20 with depressive symptoms (BDI > 13), and 22 without, were compared to 24 healthy controls in neuropsychological tasks of speed of processing (SDMT, Stroop, TMT y PASAT-BNB). RESULTS. MS patients without depressive symptoms performed significantly worse than healthy controls the Stroop (W, C and WC), and the PASAT-BNB (execution time) tests. MS patients with depressive symptoms performed significantly worse than healthy controls the Stroop (W, C and WC), SDMT, TMT (A, B and B-A), and the PASAT-BNB (execution time and errors) tests. MS patients with depressive symptoms performed significantly worse than MS patients without depressive symptoms the SDMT, TMT (A, B and B-A), and the PASAT-BNB (execution time) tests. CONCLUSIONS. MS impact was not generalized in neuropsychological performance of patients. Depressive symptoms seem to play and important role determining the speed deficit. While MS reduced speed of information processing, depressive symptoms were associated to specific cognitive deficit different from speed ones.
Authors:
G Lubrini; J A Perianez; M Rios-Lago; A Frank
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Revista de neurologia     Volume:  55     ISSN:  1576-6578     ISO Abbreviation:  Rev Neurol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706841     Medline TA:  Rev Neurol     Country:  Spain    
Other Details:
Languages:  spa     Pagination:  585-92     Citation Subset:  IM    
Affiliation:
UAM. Universidad Autonoma de Madrid. Hospital Universitario La Paz, 28046 Madrid, Espana.
Vernacular Title:
Velocidad de procesamiento en la esclerosis multiple remitente recurrente: el papel de los sintomas depresivos.
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