Document Detail


Process technology for multi-enzymatic reaction systems.
MedLine Citation:
PMID:  22531164     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In recent years, biocatalysis has started to provide an important green tool in synthetic organic chemistry. Currently, the idea of using multi-enzymatic systems for industrial production of chemical compounds becomes increasingly attractive. Recent examples demonstrate the potential of enzymatic synthesis and fermentation as an alternative to chemical-catalysis for the production of pharmaceuticals and fine chemicals. In particular, the use of multiple enzymes is of special interest. However, many challenges remain in the scale-up of a multi-enzymatic system. This review summarizes and discusses the technology options and strategies that are available for the development of multi-enzymatic processes. Some engineering tools, including kinetic models and operating windows, for developing and evaluating such processes are also introduced.
Authors:
Rui Xue; John M Woodley
Related Documents :
9773804 - Synthesis and biological activity of gold and tin compounds in ovarian cancer cells.
1670504 - Synthesis and cytotoxic activity of (e)-1-(2-nitrovinyl) and 1-[n-(tert-butylformiminyl...
9632364 - Synthesis and antitumor activity of ring a- and f-modified hexacyclic camptothecin anal...
20627724 - Synthesis and biological evaluation of indolyl chalcones as antitumor agents.
20452674 - Dimethyl titanocene y: a valuable precursor for libraries of cytotoxic titanocene deriv...
19897374 - Interaction studies between human alpha-tocopherol transfer protein and nitric oxide do...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-19
Journal Detail:
Title:  Bioresource technology     Volume:  -     ISSN:  1873-2976     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-4-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9889523     Medline TA:  Bioresour Technol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Center for Process Engineering and Technology, Department of Chemical and Biochemical Engineering, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fibroblast growth factor 23 and the heart.
Next Document:  Response of poly-phosphate accumulating organisms to free nitrous acid inhibition under anoxic and a...