| Process simulation in the pharmaceutical industry: a review of some basic physical models. | |
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MedLine Citation:
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PMID: 16447175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study reviews process modeling efforts which have been developed to elucidate the fundamental physical process underlying the manufacture and delivery of pharmaceutical dosage forms. Within the pharmaceutical industry, process models have been applied to a diverse array of physical processes at length and time scales that vary by orders of magnitude. As such, both large-scale continuum and particle-scale discrete approaches will be discussed in this study. Challenges associated with the practical application of process models within the pharmaceutical industry will be discussed, and opportunities for future research will be identified. |
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Authors:
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D M Kremer; B C Hancock |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of pharmaceutical sciences Volume: 95 ISSN: 0022-3549 ISO Abbreviation: J Pharm Sci Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-02-07 Completed Date: 2006-05-30 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 2985195R Medline TA: J Pharm Sci Country: United States |
Other Details:
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Languages: eng Pagination: 517-29 Citation Subset: IM |
Copyright Information:
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Copyright 2006 Wiley-Liss, Inc. and the American Pharmacists Association. |
Affiliation:
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Pharmaceutical Research and Development, Pfizer, Inc., Global Research and Development, Groton/New London Laboratories, Connecticut 06340, USA. douglas.m.kremer@pfizer.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Chemistry, Pharmaceutical* Drug Industry Models, Theoretical* Physical Phenomena Physics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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