Document Detail

Process of measuring in clinical medicine--implications of different definitions in clinical therapeutic studies.
MedLine Citation:
PMID:  17489029     Owner:  NLM     Status:  MEDLINE    
Often, the decision whether a patient can be considered as healthy or ill is very difficult and depends on measurements and the interpretation of the results. Therefore, it is necessary to build and establish devices that base on certain pre-considerations (who should assess the data, when and how should be measured). Additionally, these devices have to be valid, reliable and responsive. According to the literature we came to the conclusion that no uniform definition of what is 'healthy' exists. Referring to mathematical considerations we show an approach to solve this problem especially when the device is a scale. Based on the quality of the scale and of certain pre-considerations, normal ranges can be established that will help to distinguish whether patients are 'healthy' or 'ill'. In this short review we discuss the problem of the establishment of a cut-off level on the basis of devices and we try to point out a solution to solve the arising problems.
Andree Beckerling; Waldemar Braun; Michael Sommer
Related Documents :
15178519 - Reliability and motor memory.
7475029 - Reliability of individual diagnostic criterion items for psychoactive substance depende...
23124479 - In silico multi-scale model of transport and dynamic seeding in a bone tissue engineeri...
2005039 - A simple, rapid and reliable method for selecting or assessing the number of replicates...
7353289 - Automated multiple flow-injection analysis in clinical chemistry: determination of albu...
16327799 - Statistical strategies to assess reliability in ophthalmology.
10734289 - Repeated measures in clinical trials: simple strategies for analysis using summary meas...
6933859 - Canine retraction with j hook headgear.
22255919 - Experimental and theoretical study of an internally cooled bipolar electrode for rf coa...
Publication Detail:
Type:  Journal Article; Review     Date:  2007-05-04
Journal Detail:
Title:  Digestion     Volume:  75 Suppl 1     ISSN:  1421-9867     ISO Abbreviation:  Digestion     Publication Date:  2007  
Date Detail:
Created Date:  2007-05-09     Completed Date:  2007-07-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  25-31     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
IFE Institute for Research and Development at the University Witten/Herdecke, Witten, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anti-Ulcer Agents / administration & dosage*
Clinical Medicine / standards*,  trends
Dose-Response Relationship, Drug
Evidence-Based Medicine
Gastroesophageal Reflux / diagnosis,  drug therapy*
Omeprazole / administration & dosage*
Randomized Controlled Trials as Topic
Reference Values
Reproducibility of Results
Severity of Illness Index
Treatment Outcome
Reg. No./Substance:
0/Anti-Ulcer Agents; 73590-58-6/Omeprazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Institution type-dependent high prevalence of dementia in long-term care units.
Next Document:  Evaluation of GERD symptoms during therapy. Part I. Development of the new GERD questionnaire ReQues...