| Proceedings of a consensus conference: the screening of blood donors for variant CJD. | |
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MedLine Citation:
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PMID: 15067588 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since the identification, in 1996, of the first case of variant Creutzfeldt-Jakob disease (vCJD) in humans various approaches have been implemented and/or proposed to prevent this disease from being transfusion transmitted. In addition, a variety of possible laboratory-based approaches have been developed and will continue to be developed for the vCJD screening of blood donors. Various issues related to the implementation of such vCJD testing is likely to assume greater importance as diagnostic tests for vCJD becomes available for the potential screening of blood donors. The purpose of this Consensus Conference was to bring together international experts in an effort to determine which principles should guide the introduction of such testing. These experts provided the scientific and biological background of bovine spongiform encephalopathy (BSE) and vCJD, an understanding of their current epidemiology, as well as the ethical and legal issues that would impact on the implementation of a screening test for preventing the transfusion transmission of vCJD. This contentious issue is of potential considerable importance to transfusion medicine personnel worldwide, as well as to future recipients of allogeneic blood components. |
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Authors:
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Morris A Blajchman; Mindy Goldman; Kathryn E Webert; Eleftherios C Vamvakas; Judith Hannon; Gilles Delage |
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Publication Detail:
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Type: Congresses |
Journal Detail:
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Title: Transfusion medicine reviews Volume: 18 ISSN: 0887-7963 ISO Abbreviation: Transfus Med Rev Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-06 Completed Date: 2004-11-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8709027 Medline TA: Transfus Med Rev Country: United States |
Other Details:
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Languages: eng Pagination: 73-92 Citation Subset: IM |
Affiliation:
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Canadian Blood Services, Hamilton, Ontario, Canada. Blajchma@mcmaster.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Donors* Blood Transfusion / adverse effects* Cattle Consumer Product Safety Creutzfeldt-Jakob Syndrome / blood*, diagnosis*, genetics* Encephalopathy, Bovine Spongiform / transmission* Humans Mass Screening PrPSc Proteins / blood Prion Diseases / transmission* |
| Chemical | |
Reg. No./Substance:
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0/PrPSc Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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