Document Detail

Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005.
MedLine Citation:
PMID:  16514773     Owner:  NLM     Status:  MEDLINE    
The 4th Georg Rajka International Symposium on Atopic Dermatitis presented a comprehensive view of our current understanding and management of atopic dermatitis (AD). These proceedings highlight contributions related to the history of AD doctrines; genetic and epigenetic background; epidemiology; maturation of the immune system; infection and innate-adaptive immunity; epidermal inflammation, including neurogenic inflammation and pruritus; animal models; skin barrier; evidence-based therapy and education programs; prognostic and severity markers; and allergy testing. Several studies in animal models and human subjects point to impaired skin barrier function as a primary defect that facilitates the effect of environmental factors and immune dysregulation found in AD. The new frontier in AD therapy should, in the near future, reflect our better understanding of the skin barrier. The influence of environmental factors on the skin and other epithelial barriers in the perinatal period needs to be better understood to implement appropriate prevention programs.
Alain Taïeb; Jon Hanifin; Kevin Cooper; Jan D Bos; Genji Imokawa; Tim J David; Johannes Ring; Carlo Gelmetti; Alexander Kapp; Masutaka Furue; Yves de Prost; Ulf Darsow; Thomas Werfel; David Atherton; Arnold P Oranje
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Publication Detail:
Type:  Congresses    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  117     ISSN:  0091-6749     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-03     Completed Date:  2006-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  378-90     Citation Subset:  AIM; IM    
Department of Dermatology and Pediatric Dermatology, CHU de Bordeaux, Bordeaux, France.
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MeSH Terms
Child, Preschool
Dermatitis, Atopic* / epidemiology,  etiology,  genetics,  immunology
Disease Models, Animal
Mice, Inbred C57BL
Skin / immunology,  microbiology

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