Document Detail

Procedural and in-patient outcomes in patients aged 80 years or older undergoing contemporary primary percutaneous coronary intervention.
MedLine Citation:
PMID:  23253545     Owner:  NLM     Status:  In-Data-Review    
Aims: Patients aged ≥80 years are often excluded or under-represented in trials assessing treatment modalities in STEMI. We assessed in-patient outcomes in elderly patients undergoing contemporary primary PCI (PPCI). Methods and results: From Sept 2005 to July 2011 patients undergoing PPCI in our centre were identified. Demographic details, procedural data and in-patient outcomes were collated. Those aged ≥80 years were compared with those aged <80 years. In the study period 1,218 patients required PPCI, of which 224(18.4%) were ≥80 years. The elderly cohort were more likely to be female (44.3% vs. 20.3%; p<0.001), and have significant comorbidities. Times from first medical contact until TIMI 3 flow were similar between the two groups (medien 102 min vs. 109 min; p=0.19). There was no difference in rates of PCI success (97.3% vs. 98.3%; p=0.24), drug-eluting stent use (63.5% vs. 63.3%; p=1.00) and number of stents used. In-patient outcomes were worse in the elderly cohort with significantly higher rates of death (11.2% vs. 3.7%; p<0.001) and acute kidney injury (12.9% vs. 4.0%; p<0.001), with a trend towards more post-procedure cardiovascular accidents (CVA), access site complications and reinfarction. Length of stay was significantly longer in the elderly cohort (median days 5 vs. 3; p<0.001). Conclusions: Important demographic differences exist in very elderly patients presenting with STEMI compared to younger patients though procedural data and PCI success rates are similar between the two groups. Those aged ≥80 years have significantly worse in-patient outcomes though death rates are not as high as historical data suggests.
John C Murphy; Rebecca A Kozor; Gemma Figtree; Peter S Hansen; Helge H Rasmussen; Michael R Ward; Gregory I C Nelson; Ravinay Bhindi
Related Documents :
19953235 - Intra-arterial colforsin daropate for the treatment of cerebral vasospasm after aneurys...
10527435 - Perigraft air, fever, and leukocytosis after endovascular repair of abdominal aortic an...
2895995 - Effect of beta-adrenergic blockade on the growth rate of abdominal aortic aneurysms.
1703635 - New screening system for unruptured cerebral aneurysms--combination of an expert system...
1516315 - Surgical correction of foot deformities after stroke.
2609245 - Experience with pge1 in patients with postoperative trashfoot.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  8     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  912-9     Citation Subset:  IM    
Royal North Shore Hospital, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sex- and age-related differences in clinical outcome after primary percutaneous coronary interventio...
Next Document:  Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: the ...