Document Detail

Procedural and 30-day outcomes following transcatheter aortic valve implantation using the third generation (18 Fr) corevalve revalving system: results from the multicentre, expanded evaluation registry 1-year following CE mark approval.
MedLine Citation:
PMID:  19110790     Owner:  NLM     Status:  MEDLINE    
AIMS: To describe the procedural performance and 30-day outcomes following implantation using the 18 Fr CoreValve Revalving System (CRS) as part of the multicentre, expanded evaluation registry, 1-year after obtaining CE mark approval. METHODS AND RESULTS: Patients with symptomatic severe aortic stenosis and logistic Euroscore > or =15%, or age > or =75 years, or age > or =65 years associated with pre-defined risk factors, and for whom a physician proctor and a clinical specialist were in attendance during the implantation and who collected the clinical data, were included. From April 2007, to April 2008, 646 patients with a mean age of 81 +/- 6.6 years, mean aortic valve area 0.6 +/- 0.2 cm2, and logistic EuroSCORE of 23.1 +/- 13.8% were recruited. After valve implantation, the mean transaortic valve gradient decreased from 49.4 +/- 13.9 to 3 +/- 2 mmHg. All patients had paravalvular aortic regurgitation < or = grade 2. The rate of procedural success was 97%. The procedural mortality rate was 1.5%. At 30 days, the all-cause mortality rate (i.e, including procedural) was 8% and the combined rate of death, stroke and myocardial infarction was 9.3%. CONCLUSIONS: The results of this study demonstrate the high rate of procedural success and a low 30-day mortality in a large cohort of high-risk patients undergoing transcatheter aortic valve implantation (TAVI) with the CRS.
Nicolo Piazza; Eberhard Grube; Ulrich Gerckens; Peter den Heijer; Axel Linke; Olev Luha; Angelo Ramondo; Giampaolo Ussia; Peter Wenaweser; Stephan Windecker; Jean-Claude Laborde; Peter de Jaegere; Patrick W Serruys
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  4     ISSN:  1774-024X     ISO Abbreviation:  -     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-12-29     Completed Date:  2009-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  242-9     Citation Subset:  IM    
Thoraxcenter, Rotterdam, The Netherlands.
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MeSH Terms
Aged, 80 and over
Aortic Valve Insufficiency / mortality*,  surgery*,  ultrasonography
Cause of Death
Device Approval
Heart Valve Prosthesis / statistics & numerical data*
Heart Valve Prosthesis Implantation / mortality*
Postoperative Complications / mortality
Prosthesis Design
Risk Management
Severity of Illness Index
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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