Document Detail

Procalcitonin, c-reactive protein and neopterin levels in patients with coronary atherosclerosis.
MedLine Citation:
PMID:  16128367     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Recent studies demonstrate that the serum inflammatory markers increase in patients with atherosclerosis. We aimed to assess whether a difference exists between patients with acute coronary syndrome and patients with stable angina pectoris in respect to serum neopterin, procalcitonin (PCT) and C-reactive protein (CRP) levels. METHODS AND RESULTS: A total of 52 patients (42 male, 10 female) who had atherosclerosis confirmed by angiography and were being followed up for an acute coronary syndrome were recruited and for control group, 45 patients with stable angina pectoris (SA) (35 male and 10 female) who underwent coronary angiography, were examined. Serum concentrations of neopterin, CRP and PCT in the study group (acute coronary syndrome) were compared to control group (stable angina pectoris). The mean neopterin level of the study group was 22.47 +/- 2.93 nmol/l, the mean CRP level was 30.40 +/- 8.05 mg/l and the mean PCT level was 0.40 +/- 0.04 ng/ml. In control group these levels were 12.26 +/- 0.61 nmol/l (p < 0.05), 5.26 +/- 0.64 mg/l (p < 0.001) and 0.19 +/- 0.02 ng/ml (p < 0.001), respectively. CONCLUSION: In the presented study our results showed that these markers can be useful for the assessment of inflammation related to atherosclerosis.
Fulya Ilhan; Handan Akbulut; Ilgm Karaca; Ahmet Godekmerdan; Erdogan Ilkay; Vedat Bulut
Related Documents :
3154677 - Calcium channel antagonists. part ii: use and comparative properties of the three proto...
6117297 - Prognostic significance of electrocardiographic findings in angina at rest. therapeutic...
10952837 - Clinical outcomes, risk stratification and practice patterns of unstable angina and myo...
2598947 - Nocturnal angina in patients with fixed coronary stenosis. increased coronary vasoconst...
315297 - Regional effects of propranolol on intraventricular conduction in coronary artery disease.
10629407 - Use of glycoprotein iib/iiia inhibitors in patients with acute coronary syndromes under...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  60     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-30     Completed Date:  2006-02-16     Revised Date:  2009-06-11    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  361-5     Citation Subset:  IM    
Department of Immunology, Firat University, Medical Faculty Elazig, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angina Pectoris / blood
C-Reactive Protein / analysis*
Calcitonin / blood*
Case-Control Studies
Coronary Artery Disease / blood*
Glycoproteins / analysis*
Middle Aged
Neopterin / blood*
Protein Precursors / blood*
Reg. No./Substance:
0/Glycoproteins; 0/Protein Precursors; 56645-65-9/procalcitonin; 670-65-5/Neopterin; 9007-12-9/Calcitonin; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of copper and zinc on the production of homocysteine-induced extracellular matrix metallopro...
Next Document:  Protective effect of aprotinin against lung damage in patients undergoing CABG surgery.