| Procalcitonin, c-reactive protein and neopterin levels in patients with coronary atherosclerosis. | |
| | |
MedLine Citation:
|
PMID: 16128367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Recent studies demonstrate that the serum inflammatory markers increase in patients with atherosclerosis. We aimed to assess whether a difference exists between patients with acute coronary syndrome and patients with stable angina pectoris in respect to serum neopterin, procalcitonin (PCT) and C-reactive protein (CRP) levels. METHODS AND RESULTS: A total of 52 patients (42 male, 10 female) who had atherosclerosis confirmed by angiography and were being followed up for an acute coronary syndrome were recruited and for control group, 45 patients with stable angina pectoris (SA) (35 male and 10 female) who underwent coronary angiography, were examined. Serum concentrations of neopterin, CRP and PCT in the study group (acute coronary syndrome) were compared to control group (stable angina pectoris). The mean neopterin level of the study group was 22.47 +/- 2.93 nmol/l, the mean CRP level was 30.40 +/- 8.05 mg/l and the mean PCT level was 0.40 +/- 0.04 ng/ml. In control group these levels were 12.26 +/- 0.61 nmol/l (p < 0.05), 5.26 +/- 0.64 mg/l (p < 0.001) and 0.19 +/- 0.02 ng/ml (p < 0.001), respectively. CONCLUSION: In the presented study our results showed that these markers can be useful for the assessment of inflammation related to atherosclerosis. |
| | |
Authors:
|
Fulya Ilhan; Handan Akbulut; Ilgm Karaca; Ahmet Godekmerdan; Erdogan Ilkay; Vedat Bulut |
Related Documents
:
|
18041887 - Ranolazine: a new option in the management of chronic stable angina. 6693637 - Clinical and angiographic factors associated with progression of coronary artery disease. 9060797 - Association of preceding angina with in-hospital life-threatening ventricular tachyarrh... 21526047 - Vagal nerve stimulation in prevention and management of coronary heart disease. 17122197 - Cardiac effects of postconditioning depend critically on the duration of index ischemia. 17000787 - Pharmacologic evidence for the involvement of central and peripheral opioid receptors i... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta cardiologica Volume: 60 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2005 Aug |
Date Detail:
|
Created Date: 2005-08-30 Completed Date: 2006-02-16 Revised Date: 2009-06-11 |
Medline Journal Info:
|
Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
|
Languages: eng Pagination: 361-5 Citation Subset: IM |
Affiliation:
|
Department of Immunology, Firat University, Medical Faculty Elazig, Turkey. fulhan23@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angina Pectoris
/
blood C-Reactive Protein / analysis* Calcitonin / blood* Case-Control Studies Coronary Artery Disease / blood* Female Glycoproteins / analysis* Humans Male Middle Aged Neopterin / blood* Protein Precursors / blood* |
| Chemical | |
Reg. No./Substance:
|
0/Glycoproteins; 0/Protein Precursors; 56645-65-9/procalcitonin; 670-65-5/Neopterin; 9007-12-9/Calcitonin; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of copper and zinc on the production of homocysteine-induced extracellular matrix metallopro...
Next Document: Protective effect of aprotinin against lung damage in patients undergoing CABG surgery.