Document Detail


Procainamide-induced postoperative pyrexia.
MedLine Citation:
PMID:  10510015     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Procainamide is an effective antiarrhythmic that is often used to convert atrial fibrillation to normal sinus rhythm. A side effect of procainamide, rarely reported in the surgical literature, is pyrexia. The pyrexia is a manifestation of an allergic response to this medication. If unrecognized, procainamide-induced pyrexia can lead to unnecessary testing, hospitalization, and treatment. We present a case of a post-coronary artery bypass surgery patient who repeatedly displayed pyrexia when reexposed to procainamide indicating an allergic response to this drug.
Authors:
K D Murray; J J Vlasnik
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  68     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-15     Completed Date:  1999-10-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1072-4     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA. kmurray@med.unr.edu
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MeSH Terms
Descriptor/Qualifier:
Anti-Arrhythmia Agents / adverse effects*
Atrial Fibrillation / drug therapy,  etiology
Coronary Artery Bypass
Drug Hypersensitivity / diagnosis*
Fever / chemically induced*
Humans
Male
Middle Aged
Postoperative Complications / diagnosis
Procainamide / adverse effects*
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 51-06-9/Procainamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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