Document Detail

Problems in the management of opportunistic infections in patients infected with human immunodeficiency virus.
MedLine Citation:
PMID:  2182728     Owner:  NLM     Status:  MEDLINE    
Opportunistic infections ultimately occur in most patients infected with human immunodeficiency virus (HIV) and are responsible for 90% of deaths. Over the decade since the acquired immunodeficiency syndrome (AIDS) was first recognized, important advances have been made in reducing the morbidity and mortality of opportunistic infections in patients infected with HIV. These include an improved understanding of the relationship between immunologic parameters and infection, allowing the occurrence of infectious complications to be more predictable; development of prophylactic regimens and chronic suppressive regimens that are effective, well tolerated, and convenient; and emphasis on earlier diagnosis and therapeutic intervention of those infectious processes that are not prevented. These advances have allowed the quality and duration of patient survival to improve during this decade, but they can also be anticipated to alter the spectrum of clinical manifestations that health care providers are going to see during this epidemic's second decade.
H Masur
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  161     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-05-24     Completed Date:  1990-05-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  858-64     Citation Subset:  AIM; IM; X    
Critical Care Medicine Department, National Institutes of Health, Bethesda, Maryland 20892.
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MeSH Terms
HIV Infections / complications*
Opportunistic Infections / complications*,  diagnosis,  drug therapy,  prevention & control
Pneumonia, Pneumocystis / complications,  diagnosis,  drug therapy,  prevention & control

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