| Problems complicating the genetic epidemiology of rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 9002036 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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I review problems inherent in considering the genetic epidemiology of rheumatoid arthritis (RA). The major area of concern is in case definition, both in assigning criteria and in establishing time of onset of disease, since presentation fluctuates throughout life. Other problem areas include selection of case and controls and the appropriate approach to analysis. Awareness of the problems in study design and conduct is fundamental to undertaking valid studies in this area. |
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Authors:
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A J Silman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of rheumatology Volume: 24 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 1997 Jan |
Date Detail:
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Created Date: 1997-03-26 Completed Date: 1997-03-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: CANADA |
Other Details:
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Languages: eng Pagination: 194-6 Citation Subset: IM |
Affiliation:
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ARC Epidemiology Research Unit, University of Manchester, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arthritis, Rheumatoid
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epidemiology*,
genetics* Diseases in Twins / genetics Genetic Predisposition to Disease* Humans Patient Selection |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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