Document Detail


Problems arising from the use of the HLA system in paternity testing.
MedLine Citation:
PMID:  6788434     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Characterization of the HLA antigens present on lymphocytes has become an important procedure in paternity testing. This paper presents data on two cases in which the HLA antigens exhibited by the mother, child and alleged father were consistent with paternity but where the other genetic markers clearly showed exclusion of paternity. The use of HLA data alone to calculate probability of paternity in these two cases produced misleading figures. Caution must be exercised in using HLA results to calculate the probability of paternity, especially when there is reason to believe that the alleged and natural fathers are relatives.
Authors:
E G Reisner; J M MacQueen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and laboratory haematology     Volume:  3     ISSN:  0141-9854     ISO Abbreviation:  Clin Lab Haematol     Publication Date:  1981  
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907061     Medline TA:  Clin Lab Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Gene Frequency
HLA Antigens
Haploidy
Humans
Lymphocytes / immunology
Male
Paternity*
Probability
Rh-Hr Blood-Group System
Chemical
Reg. No./Substance:
0/HLA Antigens; 0/Rh-Hr Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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