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Probiotics prevent growth deficit of colon wall strata of malnourished rats post-lactation.
MedLine Citation:
PMID:  22801377     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The objective of this study was to analyze morphometrically the colon wall strata of malnourished rats supplemented with probiotics. Sixteen recently weaned Wistar rats (Rattus norvegicus) were distributed into four groups: animals that received commercial chow (G1, n = 4); animals that received the same feed as G1 and were supplemented with probiotics (G2, n = 4); animals that received chow with 4% of proteins (G3, n = 4); animals that received the same feed as G3 and were supplemented with probiotics (G4, n = 4). After 12 weeks, the proximal colon was collected and submitted to histological processing. Three-µm cuts were stained with H.E., Periodic Acid Schifff (P.A.S.) + diasthasis solution and Alcian Blue (A.B.) pH 2.5 and pH 1.0. The morphometric analysis of the intestinal wall showed that the supplementation with ABT-4 probiotic culture prevents the growth deficit of colon wall strata that normally occurs in malnourished rats right after lactation. Besides, no alteration was observed in the proportion of the number of globet cells in relation to the number of enterocytes in malnourished rats, regardless of the supplementation with probiotics.
Authors:
Dirlene P Lima; Jorge F de Azevedo; Catchia Hermes-Uliana; Gilberto Alves; Débora M G Sant'ana; Eduardo J A Araújo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-17
Journal Detail:
Title:  Anais da Academia Brasileira de Ciencias     Volume:  -     ISSN:  1678-2690     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503280     Medline TA:  An Acad Bras Cienc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Programa em Ciência Animal, Universidade Paranaense, Umuarama, PR, Brasil, 87502-210.
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