Document Detail

Probiotics and prebiotics in pediatrics: where are we now?
MedLine Citation:
PMID:  17990574     Owner:  NLM     Status:  MEDLINE    
In recent years, probiotics and prebiotics have become a hot topic. There are an increasing number of health benefits attributed to them. However, only a few of the benefits have been confirmed in well-conducted randomized controlled trials. This paper was written to evaluate the evidence on the effect of administration of probiotics and prebiotics in children. Electronic databases and the reference lists of publications were searched for randomized controlled trials or their meta-analyses (all up until April 2007). Based on the available evidence, to date, the most extensively studied application and the best documented is the use of some probiotic strains for the treatment of acute infectious diarrhea and prevention of antibiotic-associated diarrhea. Many other benefits, both of probiotics and prebiotics, are largely unproven, but there is a growing body of scientific evidence in support of such benefits. Guidance is needed as to which agent to use, timing, dosage and mode of administration.
Hania Szajewska
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  49     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2007 Jul-Sep
Date Detail:
Created Date:  2007-11-09     Completed Date:  2008-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  231-44     Citation Subset:  IM    
2nd Department of Pediatrics, Medical University of Warsaw, Warsaw, Poland.
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MeSH Terms
Anti-Bacterial Agents / adverse effects,  therapeutic use*
Child, Preschool
Cross Infection / prevention & control*
Diarrhea / chemically induced,  drug therapy,  prevention & control
Enterocolitis, Necrotizing / prevention & control*
Infant, Newborn
Meta-Analysis as Topic
Probiotics / administration & dosage,  therapeutic use*
Randomized Controlled Trials as Topic
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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