Document Detail

Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
MedLine Citation:
PMID:  8986316     Owner:  NLM     Status:  MEDLINE    
Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism. There has been only one other published case of induction of mania in a patient treated with nefazodone. This report describes a second case of probable induction of mania with nefazodone therapy and briefly reviews clinical and theoretical considerations involved in this process.
H A Zaphiris; G D Blaisdell; D M Jermain
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists     Volume:  8     ISSN:  1040-1237     ISO Abbreviation:  Ann Clin Psychiatry     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-04-09     Completed Date:  1997-04-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8911021     Medline TA:  Ann Clin Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  207-10     Citation Subset:  IM    
Department of Psychiatry and Behavioral Sciences, Texas A&M University College of Medicine, Scott & White Hospital and Clinic, Temple 76508, USA.
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MeSH Terms
Antidepressive Agents, Second-Generation / adverse effects*,  therapeutic use
Antidepressive Agents, Tricyclic / administration & dosage,  adverse effects
Bipolar Disorder / chemically induced*,  diagnosis,  psychology
Depressive Disorder / diagnosis,  drug therapy*,  psychology
Desipramine / administration & dosage,  adverse effects
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Therapy, Combination
Middle Aged
Patient Care Team
Premenstrual Syndrome / diagnosis,  drug therapy*,  psychology
Triazoles / adverse effects*,  therapeutic use
Reg. No./Substance:
0/Antidepressive Agents, Second-Generation; 0/Antidepressive Agents, Tricyclic; 0/Triazoles; 50-47-5/Desipramine; 83366-66-9/nefazodone

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