Document Detail


Probability of urinary tract infection in infants with ureteropelvic junction obstruction: is antibacterial prophylaxis really needed?
MedLine Citation:
PMID:  21520006     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In infants with ureteropelvic junction obstruction (UPJO), the risk of urinary tract infection (UTI) is unknown, and there is a lack of prospective studies showing definitive evidence regarding the benefits and necessity of antibiotic prophylaxis. The aim of this study was to assess the risk of UTI in infants with UPJO and to determine whether the risk varies according to the degree of hydronephrosis. Infants with hydronephrosis detected prenatally or within the postnatal 28th day and who had no previous history of UTI were followed prospectively without antibacterial prophylaxis. Imaging studies were performed according to our Pediatric Uro-Nephrology Study Group protocol. Dimercaptosuccinate (DMSA) scintigraphy was performed in all infants at the end of 1 year of follow-up. Eighty-four infants (56 boys, 28 girls) were included in the study. The distribution of patients in each hydronephrosis grading group was incidentally similar. Within a median follow-up period of 18 (12-24) months, none of the patients had UTI. Furthermore, no pyelonephritic scar was found on DMSA scans in any patient. We conclude that prophylactic antibiotic usage is not indicated in infants with UPJO, regardless of the severity of hydronephrosis, as the risk of UTI is minimal in this population.
Authors:
Ali Islek; Ayfer Gür Güven; Mustafa Koyun; Sema Akman; Emel Alimoglu
Related Documents :
11593296 - Preeclampsia: from epidemiological observations to molecular mechanisms.
23244456 - Coparenting quality during the first three months after birth: the role of infant sleep...
3939146 - Cost-effectiveness of immunization in the gambia.
21211856 - Making targeted screening for infant hearing loss an effective option in less developed...
19492926 - Prenatal diagnosis and postnatal management of meconium peritonitis.
9396576 - Low birth weight and subsequent male subfertility.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-26
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  -     ISSN:  1432-198X     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Pediatrics, Akdeniz University, 07070, Antalya, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  HMME-based PDT restores expression and function of transporter associated with antigen processing 1 ...
Next Document:  Kidney transplantation in childhood: mental health and quality of life of children and caregivers.