| Probability models and computational models for ANOVA in multicenter clinical trials. | |
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MedLine Citation:
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PMID: 12921396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multicenter trials are usually analyzed by fixed-effects, two-way analysis of variance. A mixed-effects computation with random treatment-by-center interaction may produce better results even if this interaction is considered truly to be a fixed effect. It may be more appropriate, however, to consider the treatment-by-center interaction to be a random effect, anyway. |
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Authors:
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Thomas Permutt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of biopharmaceutical statistics Volume: 13 ISSN: 1054-3406 ISO Abbreviation: J Biopharm Stat Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-08-18 Completed Date: 2004-03-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9200436 Medline TA: J Biopharm Stat Country: United States |
Other Details:
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Languages: eng Pagination: 495-505 Citation Subset: IM |
Affiliation:
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Food and Drug Administration, Rockville, Maryland 20857, USA. permuttT@cder.fda.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Mathematical Computing* Models, Statistical* Multicenter Studies as Topic / statistics & numerical data* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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