Document Detail


Pro-inflammatory cytokines in acute coronary syndromes: from bench to bedside.
MedLine Citation:
PMID:  16750416     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cytokines are produced in a variety of tissues and regulate the expression of a number of inflammatory molecules, leading to destabilization and finally rupture of vulnerable atheromatic plaques. They also participate in the pathophysiology of acute coronary syndromes (ACS) by direct effects on myocardial contractility and apoptosis. At a clinical level, circulating cytokines have a prognostic role since they are useful markers predicting future coronary events in patients with advanced atherosclerosis and in patients after ACS.
Authors:
Dimitris Tousoulis; Charalambos Antoniades; Nikolaos Koumallos; Christodoulos Stefanadis
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-06-05
Journal Detail:
Title:  Cytokine & growth factor reviews     Volume:  17     ISSN:  1359-6101     ISO Abbreviation:  Cytokine Growth Factor Rev.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-18     Completed Date:  2006-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612306     Medline TA:  Cytokine Growth Factor Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  225-33     Citation Subset:  IM    
Affiliation:
1st Cardiology Unit, Athens University Medical School, Athens, Greece. tousouli@med.uoa.gr
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Atherosclerosis / immunology
Coronary Disease / diagnosis,  drug therapy,  immunology*
Cytokines / antagonists & inhibitors,  metabolism,  physiology*
Humans
Inflammation Mediators / antagonists & inhibitors,  metabolism,  physiology
Myocardial Infarction / diagnosis,  immunology
Prognosis
Syndrome
Chemical
Reg. No./Substance:
0/Cytokines; 0/Inflammation Mediators

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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