Document Detail


Privacy technology to support data sharing for comparative effectiveness research: a systematic review.
MedLine Citation:
PMID:  23774511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Effective data sharing is critical for comparative effectiveness research (CER), but there are significant concerns about inappropriate disclosure of patient data. These concerns have spurred the development of new technologies for privacy-preserving data sharing and data mining. Our goal is to review existing and emerging techniques that may be appropriate for data sharing related to CER.
MATERIALS AND METHODS: We adapted a systematic review methodology to comprehensively search the research literature. We searched 7 databases and applied 3 stages of filtering based on titles, abstracts, and full text to identify those works most relevant to CER.
RESULTS: On the basis of agreement and using the arbitrage of a third party expert, we selected 97 articles for meta-analysis. Our findings are organized along major types of data sharing in CER applications (ie, institution-to-institution, institution hosted, and public release). We made recommendations based on specific scenarios.
LIMITATION: We limited the scope of our study to methods that demonstrated practical impact, eliminating many theoretical studies of privacy that have been surveyed elsewhere. We further limited our study to data sharing for data tables, rather than complex genomic, set valued, time series, text, image, or network data.
CONCLUSION: State-of-the-art privacy-preserving technologies can guide the development of practical tools that will scale up the CER studies of the future. However, many challenges remain in this fast moving field in terms of practical evaluations and applications to a wider range of data types.
Authors:
Xiaoqian Jiang; Anand D Sarwate; Lucila Ohno-Machado
Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Medical care     Volume:  51     ISSN:  1537-1948     ISO Abbreviation:  Med Care     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-06-24     Completed Date:  2013-09-13     Revised Date:  2013-12-09    
Medline Journal Info:
Nlm Unique ID:  0230027     Medline TA:  Med Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S58-65     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Comparative Effectiveness Research / organization & administration*
Confidentiality*
Cooperative Behavior
Databases, Bibliographic
Humans
Software*
Grant Support
ID/Acronym/Agency:
K99 LM011392/LM/NLM NIH HHS; K99LM011392/LM/NLM NIH HHS; R00 LM011392/LM/NLM NIH HHS; R01 HS019913/HS/AHRQ HHS; R01HS019913/HS/AHRQ HHS; U54 HL108460/HL/NHLBI NIH HHS; U54HL108460/HL/NHLBI NIH HHS; UH2HL108785/HL/NHLBI NIH HHS; UL1TR00010003/TR/NCATS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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