Document Detail


Priority allocation of cadaver kidneys to highly presensitized transplant recipients. Collaborative Transplant Study.
MedLine Citation:
PMID:  3075914     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Within a prospective program of priority kidney allocation to highly presensitized recipients, 100 first and second cadaver transplants were performed from April 1985 to July 1987. The patient survival rate was 93% at 1 year. Graft survival at 1 year was 71% for first transplants and 68% for second transplants. There was a statistically significant correlation of graft outcome with matching for HLA-DR (P less than 0.02) and for HLA-B and -DR (P less than 0.02). The results demonstrate that multicenter cooperation is advantageous for the transplantation of highly presensitized recipients and that acceptable success rates can be obtained.
Authors:
G Opelz
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Transplant international : official journal of the European Society for Organ Transplantation     Volume:  1     ISSN:  0934-0874     ISO Abbreviation:  Transpl. Int.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1989-09-01     Completed Date:  1989-09-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8908516     Medline TA:  Transpl Int     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  2-5     Citation Subset:  IM    
Affiliation:
Institut für Immunologie der Universität, Heidelberg, Federal Republic of Germany.
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MeSH Terms
Descriptor/Qualifier:
Antilymphocyte Serum / isolation & purification
Clinical Trials as Topic
Graft Survival
HLA Antigens
Histocompatibility Testing
Humans
Immunization
Kidney Transplantation*
Multicenter Studies as Topic
Prospective Studies
Chemical
Reg. No./Substance:
0/Antilymphocyte Serum; 0/HLA Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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