Document Detail


Prior restenosis predicts restenosis after coronary angioplasty of a new significant narrowing.
MedLine Citation:
PMID:  1951074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the influence of a history of restenosis on subsequent restenosis after percutaneous transluminal coronary angioplasty (PTCA) of a new significant narrowing, the records of 100 patients who underwent successful PTCA at another site ("new narrowing PTCA") greater than or equal to 2 months after successful initial PTCA were retrospectively reviewed. Patients were grouped according to whether initial PTCA resulted in restenosis, which was determined by angiographic follow-up greater than or equal to 3 months after initial PTCA. Patients in group 1 did not have restenosis after initial PTCA (n = 50), whereas patients in group 2 did (n = 40). All patients were followed for recurrent symptoms, with serial exercise tests, for greater than or equal to 6 months after new narrowing PTCA. Clinically suspected and angiographically confirmed restenosis occurred in 11 of 50 (22%) patients and 12 of 63 (19%) narrowings in group 1, and in 20 of 40 (50%) patients and 22 of 48 (46%) narrowings in group 2 (p less than 0.01 for patients, p less than 0.002 for narrowings). Multivariate analysis identified that prior restenosis (p less than 0.02, odds ratio 3.4), left anterior descending artery location of stenosis (p less than 0.04, odds ratio 3.0), and severity of stenosis before PTCA (p less than 0.02, odds ratio 1.8) were independently associated with restenosis after new narrowing PTCA. In conclusion, prior restenosis is an independent risk factor for subsequent restenosis after new narrowing PTCA.
Authors:
S J Bresee; A K Jacobs; G R Garber; N A Ruocco; R M Mills; B A Bergelson; T J Ryan; D P Faxon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  68     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1991-11-27     Completed Date:  1991-11-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1158-62     Citation Subset:  AIM; IM    
Affiliation:
Evans Memorial Department of Clinical Research, Boston University Medical Center, Massachusetts.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography
Coronary Disease / pathology,  radiography,  therapy*
Coronary Vessels / pathology
Female
Humans
Male
Middle Aged
Recurrence

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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