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Principles and emerging applications of nanomagnetic materials in medicine.
MedLine Citation:
PMID:  22488879     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The development of nanometer-scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications of these materials are rapidly becoming important in medicine and enable targeted therapies and diagnostics. At the same time, specific applications add focus to the development of novel magnetic materials and facilitate a deeper understanding of the physical mechanisms behind their function. This review presents a broad, nontechnical overview of the basis of magnetism in materials at the nanometer scale and describes how these materials are created, characterized, and used. Specific emerging applications in medical diagnostics and therapies are discussed, including cancer cell targeting for thermal ablation, tissue engineering, and three-dimensional noninvasive molecular imaging. Challenges in these fields are discussed, including the toxicity and delivery of magnetic nanomaterials and the sensitivity of imaging and therapeutic techniques. The development of novel nanomagnetic nanomaterials should continue to accelerate as new applications are identified and researchers uncover new mechanisms to increase and modulate magnetism at the nanometer scale. WIREs Nanomed Nanobiotechnol 2012. doi: 10.1002/wnan.1169 For further resources related to this article, please visit the WIREs website.
Authors:
Veronica Clavijo-Jordan; Vikram D Kodibagkar; Scott C Beeman; Bradley D Hann; Kevin M Bennett
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-9
Journal Detail:
Title:  Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology     Volume:  -     ISSN:  1939-0041     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101508311     Medline TA:  Wiley Interdiscip Rev Nanomed Nanobiotechnol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.
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