Document Detail


Principles of DNA separation with capillary electrophoresis.
MedLine Citation:
PMID:  11296917     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During the last decade, capillary electrophoresis (CE) of DNA has undergone rapid development. This improvement was especially important for DNA sequencing, where CE has now become a standard method facilitating to decipher several genomes within a very short time. Here, we give a review of the fundamentals of DNA separation in CE and the major factors influencing the performance.
Authors:
C Heller
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Electrophoresis     Volume:  22     ISSN:  0173-0835     ISO Abbreviation:  Electrophoresis     Publication Date:  2001  
Date Detail:
Created Date:  2001-04-11     Completed Date:  2001-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8204476     Medline TA:  Electrophoresis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  629-43     Citation Subset:  IM    
Affiliation:
Max-Planck-Institut für molekulare Genetik, Berlin-Dahlem, Germany. heller@biochip.com
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MeSH Terms
Descriptor/Qualifier:
DNA / isolation & purification*
Electrophoresis, Agar Gel
Electrophoresis, Capillary / methods*
Electrophoresis, Polyacrylamide Gel
Gels
Models, Chemical
Molecular Weight
Osmolar Concentration
Polymers
Surface Properties
Viscosity
Chemical
Reg. No./Substance:
0/Gels; 0/Polymers; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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