Document Detail


Princess takamatsu symposium on DNA repair and human cancers.
MedLine Citation:
PMID:  20460534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The 40th International Symposium of the Princess Takamatsu Cancer Research Fund, entitled "DNA Repair and Human Cancers," was held on November 10-12, 2009 at Hotel Grand Palace, Tokyo, Japan. The meeting focused on the role of DNA repair in preventing mutations by endogenous and exogenous DNA damage and increasing the efficacy of chemotherapeutic agents by interfering with DNA repair. The 14 presentations by the speakers from the United States, four from the United Kingdom, one each from Italy, The Netherlands, and France, and 13 from Japan, covered most aspects of DNA repair, spanning DNA damage, molecular structures of repair enzymes, and clinical studies on inhibition of DNA repair processes. Extensive time was reserved for discussions with the active participation of the 150 invited Japanese scientists. The choice of a symposium on DNA repair in human cancers resulted in part from the excellent basic and clinical studies that have been carried out for many years in Japan, and the general lack of recognition versus the importance of DNA repair in understanding carcinogenesis.
Authors:
Lawrence A Loeb; Susumu Nishimura
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Publication Detail:
Type:  Congresses; Research Support, Non-U.S. Gov't     Date:  2010-05-11
Journal Detail:
Title:  Cancer research     Volume:  70     ISSN:  1538-7445     ISO Abbreviation:  Cancer Res.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  2010-06-17     Revised Date:  2011-06-15    
Medline Journal Info:
Nlm Unique ID:  2984705R     Medline TA:  Cancer Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4269-73     Citation Subset:  IM    
Copyright Information:
Copyright 2010 AACR.
Affiliation:
Departments of Pathology and Biochemistry, University of Washington, Seattle, WA 98195-7705, USA. laloeb@u.washington.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
DNA Damage
DNA Repair*
Humans
Mutation
Neoplasms / genetics*
Grant Support
ID/Acronym/Agency:
R01 CA115802-05/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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