Document Detail

Priming of anesthesia circuit with xenon for closed circuit anesthesia.
MedLine Citation:
PMID:  9012909     Owner:  NLM     Status:  MEDLINE    
Xenon is an inert gas with a practical anesthetic potency (1 MAC = 71%). Because it is very expensive, the use of closed circuit anesthesia technique is ideal for the conduction of xenon anesthesia. Here we describe our methods of starting closed circuit anesthesia without excessive waste of xenon gas. We induce anesthesia with intravenous agents, and after endotracheal intubation, denitrogenate the patient for approximately 30 min with a high flow of oxygen. This is done to minimize accumulation of nitrogen in the anesthesia circuit during the subsequent closed-circuit anesthesia with xenon. Anesthesia is maintained with an inhalational anesthetic during this period. Then, we discontinue the inhalation agent and start xenon. For this transition, we feel it is unacceptable to simply administer xenon at a high flow until the desired end-tidal concentration is reached because it is too costly. Instead we set up another machine with its circuit filled in advance (i.e., primed) with at least 60% xenon in oxygen and switch the patient to this machine. To prime the circuit, we push xenon using a large syringe into a circuit, which was prefilled with oxygen. Oxygen inside the circuit is pushed out before it is mixed with xenon, and xenon waste will thus be minimized. In this way, we can achieve close to 1 MAC from the beginning of xenon anesthesia, and thereby minimize the risk of light anesthesia and awareness during transition from denitrogenation to closed-circuit xenon anesthesia.
H Saito; M Saito; T Goto; S Morita
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  21     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-04-17     Completed Date:  1997-04-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  IM    
Department of Biomedical Engineering, Teikyo University, School of Medicine, Ichihara Hospital, Japan.
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MeSH Terms
Anesthesia, Closed-Circuit / economics,  standards*,  trends
Anesthetics, Inhalation*
Cost-Benefit Analysis
Oxygen / administration & dosage
Reg. No./Substance:
0/Anesthetics, Inhalation; 7440-63-3/Xenon; 7782-44-7/Oxygen

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