Document Detail


Primate models of anxiety. Longitudinal perspectives.
MedLine Citation:
PMID:  8748378     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In summary, VFD subjects appear to have sustained long-term behavioral and biologic sequelae following disruption of normative maternal-infant attachment patterns. The sequelae are primarily manifest as stable anxiety or affective traits and, from a biologic perspective, are most analogous to recent data that have emerged from studies of patients with PTSD. Multiple abnormalities are observed of systems directly involved in affect regulation. Further studies are required to clarify the pathologic ontogeny of the VFD condition and its potential relevance to human psychopathology.
Authors:
J D Coplan; L A Rosenblum; J M Gorman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The Psychiatric clinics of North America     Volume:  18     ISSN:  0193-953X     ISO Abbreviation:  Psychiatr. Clin. North Am.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-09-26     Completed Date:  1996-09-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7708110     Medline TA:  Psychiatr Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  727-43     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Anxiety Disorders / physiopathology,  psychology*
Arousal / physiology
Brain / physiopathology
Child
Child, Preschool
Disease Models, Animal*
Female
Humans
Infant
Male
Maternal Deprivation
Mother-Child Relations
Neurotransmitter Agents / physiology
Personality / physiology
Primates
Receptors, Neurotransmitter / physiology
Social Environment
Grant Support
ID/Acronym/Agency:
MH 15965/MH/NIMH NIH HHS; MH 42545/MH/NIMH NIH HHS; MH-00416/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Neurotransmitter Agents; 0/Receptors, Neurotransmitter

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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