Document Detail

Primary yolk sac tumor of the omentum: a case report and review of the literature.
MedLine Citation:
PMID:  18648830     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Extraovarian yolk sac tumors (YSTs) arising in the omentum represent an exceedingly rare malignancy. CASE: A 37-year-old Korean woman was admitted with a history of lower abdominal pain of 3 weeks duration. Pelvic computerized tomography (CT) scanning reported a bilateral ovarian malignancy with peritoneal seeding. Exploration findings revealed a greater omental mass and the result of frozen biopsy was adenocarcinoma or mesothelioma. She was treated with supracolic omentectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymph node dissection, multiple peritoneal biopsies and appendectomy. Histological evaluation of the specimen after operation exhibited typical patterns of YST and stained for alpha-fetoprotein (AFP) and cytokeratin. Four courses of bleomycin, etoposide, and cisplatin (BEP) combination chemotherapy repeated every 3 weeks were added to therapy and she has remained free of disease for 1 year after completion of the therapy. CONCLUSION: To our knowledge this is the fourth case of primary omental YST. A review of the literature indicates that the diagnosis of YST requires proper evaluations of tumor makers and a skilled pathologist for analysis of frozen sections.
Sang-Wook Kim; Ju-Hee Park; Myung-Chul Lim; Jeong-Yeol Park; Chong-Woo Yoo; Sang-Yoon Park
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2008-07-22
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  279     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-12-31     Completed Date:  2009-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  189-92     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Bleomycin / administration & dosage
Cisplatin / administration & dosage
Endodermal Sinus Tumor / diagnosis*,  pathology,  therapy
Etoposide / administration & dosage
Fallopian Tubes / surgery
Keratins / analysis
Lymph Node Excision
Omentum* / pathology,  surgery
Peritoneal Neoplasms / diagnosis*,  pathology,  therapy
Peritoneum / pathology
Tomography, X-Ray Computed
alpha-Fetoproteins / analysis
Reg. No./Substance:
0/BEP protocol; 0/alpha-Fetoproteins; 11056-06-7/Bleomycin; 15663-27-1/Cisplatin; 33419-42-0/Etoposide; 68238-35-7/Keratins

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