Document Detail


Primary urinary tract infection in infants: prophylaxis for uncomplicated pyelonephritis.
MedLine Citation:
PMID:  17371343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Urinary tract infection (UTI) is one of the most common causes of unexplained fever in infants with a reported prevalence range of 5-11%. The clinical and laboratory findings were reviewed, and diagnosis and treatment for 95 infants with primary UTI were evaluated in this study. METHODS: All patients underwent renal ultrasonography, voiding cystourethrogram and 99mTc dimercaptosuccinic acid (DMSA) scan during hospitalization before treatment, with treatment consisting of 2- or 4-week appropriated antibiotic therapy for the patients associated upper UTI, followed by a second DMSA scan 6 months after therapy. RESULTS: In the present study the main symptom of UTI in infants was fever. High white blood cell count was not necessarily present, and urinalysis was also an imperfect diagnostic tool for discriminating UTI. In addition, colony count from urine culture and kidney ultrasonography was not efficacious in terms of predicting the occurrence of pyelonephritis. Intravenous antibiotic for 1 week followed by 3 weeks of the same oral antibiotic provided good prophylaxis for uncomplicated pyelonephritis. CONCLUSION: Four weeks of antibiotic treatment resulted in good recovery from pyelonephritis in the present sample of infant primary UTI cases. voiding cystourethrogram, DMSA and ultrasonography scanning should be performed in primary infant UTI.
Authors:
Kong-Sang Wan; Chih-Kuang Liu; Li-Hui Chen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephrology (Carlton, Vic.)     Volume:  12     ISSN:  1320-5358     ISO Abbreviation:  Nephrology (Carlton)     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-20     Completed Date:  2007-05-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9615568     Medline TA:  Nephrology (Carlton)     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  178-81     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Taipei City Hospital, Yangming Branch and School of Medicine, National Yang-Ming University, Tapei, Taiwan. gwan1998@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / therapeutic use*
Escherichia coli / isolation & purification
Female
Fever of Unknown Origin / drug therapy*,  microbiology,  pathology
Follow-Up Studies
Humans
Infant
Infant, Newborn
Klebsiella pneumoniae / isolation & purification
Leukocyte Count
Male
Morganella morganii / isolation & purification
Pseudomonas aeruginosa / isolation & purification
Pyelonephritis / microbiology,  pathology,  prevention & control*
Radiopharmaceuticals / diagnostic use
Technetium Tc 99m Dimercaptosuccinic Acid / diagnostic use
Time Factors
Treatment Outcome
Ultrasonography / methods
Urinary Tract Infections / blood,  complications,  diagnosis*,  drug therapy*,  microbiology
Urine / microbiology
Urography / methods
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Radiopharmaceuticals; 65438-08-6/Technetium Tc 99m Dimercaptosuccinic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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