Document Detail

Primary thyroid lympoma: diagnostic and therapeutic dilemmas.
MedLine Citation:
PMID:  20620043     Owner:  NLM     Status:  In-Process    
Primary thyroid lymphomas (PTL) are very rare tumors, typically presenting as a rapidly enlarging, painless thyroid mass, which may cause pressure symptoms of the aerodigestive tract. Preoperative diagnosis can be established by using modern imaging methods (mainly ultrasonography) and FNA with immunohistochemistry and flow cytometry. Open (surgical) biopsy may be indicated to confirm the diagnosis and identify the subtype of PTL. Therapeutic strategies are distinct from other thyroid malignancies, and include local therapy alone (surgery or radiotherapy or surgery plus radiotherapy) or - most commonly - combined multimodality treatment (mainly chemoradiation therapy). Management should be tailored to the individual patient; treatment-related morbidity should be taken into account. A high index of suspicion from the part of the clinician is required to achieve early diagnosis and prompt treatment of this potentially curable thyroid malignancy.
George H Sakorafas; Panayiottis Kokkoris; David R Farley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgical oncology     Volume:  19     ISSN:  1879-3320     ISO Abbreviation:  Surg Oncol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9208188     Medline TA:  Surg Oncol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e124-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece.
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