| Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency. | |
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MedLine Citation:
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PMID: 8796220 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parotitis and disappearance of autoantibodies. A possible role for sulphasalazine in the induction of autoimmunity in this case is discussed. |
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Authors:
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A Steuer; D J McCrea; C B Colaco |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Postgraduate medical journal Volume: 72 ISSN: 0032-5473 ISO Abbreviation: Postgrad Med J Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-10-11 Completed Date: 1996-10-11 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0234135 Medline TA: Postgrad Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 499-500 Citation Subset: IM |
Affiliation:
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Central Middlesex Hospital, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Azathioprine / therapeutic use Colitis, Ulcerative / complications*, drug therapy Gastrointestinal Agents / adverse effects Humans IgA Deficiency / chemically induced, complications* Immunosuppressive Agents / therapeutic use Male Prednisolone / therapeutic use Sjogren's Syndrome / complications* Sulfasalazine / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Gastrointestinal Agents; 0/Immunosuppressive Agents; 446-86-6/Azathioprine; 50-24-8/Prednisolone; 599-79-1/Sulfasalazine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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