| Primary Sjögren's syndrome : time for prospective cohorts. | |
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MedLine Citation:
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PMID: 22208655 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Many important clinical questions concerning primary Sjögren's syndrome (pSS) remains, that can only be adequately addressed by prospective cohorts. Thus, a better knowledge of the clinical outcome, the course of disease activity and the risk factors of lymphoma requires the setting up of cohorts with biobanks. The homogeneous collection of clinical data, disease activity, patient-related outcome, and biological samples, including DNA, RNA and serum, is definitively mandatory to determine new biological prognostic factors and identify disease activity markers. Three large prospective cohorts have already started to enroll patients with pSS. This will be highly invaluable for scientists and clinicians to gain a better insight into the pathogenesis of pSS, as well as to identify prognostic markers and new therapeutic targets. |
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Authors:
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Jacques-Eric Gottenberg; Xavier Mariette |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-2 |
Journal Detail:
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Title: Current pharmaceutical biotechnology Volume: - ISSN: 1873-4316 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100960530 Medline TA: Curr Pharm Biotechnol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Service de Rhumatologie, Hôpitaux Universitaires de Strasbourg, 1 avenue Molière, 67000 Strasbourg. jacques-eric.gottenberg@chru-strasbourg.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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