Document Detail

Primary surgical closure of ventricular septal defect in the first year of life: results in 128 infants.
MedLine Citation:
PMID:  6707379     Owner:  NLM     Status:  MEDLINE    
Between January 1973 and July 1981, 128 patients less than 1 year of age with failure to thrive, congestive heart failure or pulmonary artery hypertension underwent primary repair of a ventricular septal defect. The hospital mortality rate was 7.8% (10 of 128), and the late mortality rate was 2.3% (3 of 128). Mortality was highest among younger infants with preexisting respiratory problems or a hemodynamically significant residual lesion postoperatively. Complications included a large residual shunt in eight (6.2%), transient neurologic problems in five (3.9%) and persistent complete heart block in three (2.3%). Lung biopsy specimens obtained from 49 patients showed pulmonary vascular abnormalities in all. Complete right bundle branch block developed in 74 (64%) and bifascicular block appeared in 11 (9%). Recatheterization in 70 patients (55%) showed normal pulmonary artery pressures in all but 2 patients with a large residual shunt. Complete closure of the defect had been achieved in 49 (70%), and a hemodynamically insignificant shunt remained in 19 (27%). Patients without significant hemodynamic residua were asymptomatic and tended to accelerate in growth after surgery.
S B Yeager; M D Freed; J F Keane; W I Norwood; A R Castaneda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  3     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-05-17     Completed Date:  1984-05-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1269-76     Citation Subset:  IM    
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MeSH Terms
Age Factors
Diagnostic Errors
Heart Catheterization
Heart Septal Defects, Ventricular / physiopathology,  surgery*
Infant, Newborn
Lung / pathology
Postoperative Complications / mortality

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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