Document Detail

Primary surgical closure of large ventricular septal defects in small infants.
MedLine Citation:
PMID:  1540054     Owner:  NLM     Status:  MEDLINE    
Herein, a policy of primary surgical closure of large ventricular septal defects in infants is reviewed. Forty-eight infants met criteria for inclusion in the study, and were divided into two groups based on weight: group 1 infants weighted 4 kg or less (n = 23), and group 2 infants weighed more than 4 kg (n = 25). Both groups had similar variation in ventricular septal defect location (paramembranous versus muscular) and number (single versus multiple), as well as incidence of major associated extracardiac diseases. No early deaths occurred in group 1, compared with 1 infant (4%) in group 2. Major complications occurred similarly in both groups (9% versus 12%). There were two late deaths in group 1 (9%) and none in group 2. No surviving patients have required a second ventricular septal defect operation, and the majority no longer receive anticongestive therapies. These results indicate that primary surgical closure of large ventricular septal defects, even multiple muscular defects, can be performed in very small infants with no difference in mortality or serious complication rates compared with larger infants. Protracted medical efforts to achieve larger size before primary repair and palliative pulmonary artery banding are not necessary.
J T Hardin; A D Muskett; C E Canter; T C Martin; T L Spray
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  53     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-04-01     Completed Date:  1992-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  397-401     Citation Subset:  AIM; IM    
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
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MeSH Terms
Body Weight
Heart Septal Defects, Ventricular / mortality,  pathology,  surgery*
Infant, Newborn
Postoperative Care
Postoperative Complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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