| Primary squamous cell carcinoma of the ovary associated with endometriosis. | |
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MedLine Citation:
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PMID: 19782981 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To analyze the clinical, therapeutic, and pathologic features of published cases presenting primary squamous cell carcinoma (SCC) of the ovary associated with endometriosis. METHODS: A case report, 15 cases of infiltrating SCC of the ovary associated with or arising from endometriosis, and 1 case of synchronous carcinoma in situ in the cervix and ovary from a review of the literature were studied. RESULTS: Young age, advanced stage of the disease, and hypogastric pain were frequent at the time of diagnosis. There was no ascites, but infiltration of neighboring organs was common. The tumor was associated with 80% patient mortality in the first few months. Adjuvant chemotherapy with paclitaxel and carboplatin or cisplatin appeared to improve the results. CONCLUSION: Primary SCC of the ovary associated with endometriosis is extremely rare and has a poor prognosis. The best therapeutic results are obtained with paclitaxel and carboplatin or cisplatin after radical surgery. |
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Authors:
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Pedro Aci?n; Maida Abad; Maria-Jos? Mayol; Salvador Garcia; Javier Garde |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 108 ISSN: 1879-3479 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-16 Completed Date: 2010-03-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: Ireland |
Other Details:
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Languages: eng Pagination: 16-20 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, San Juan University Hospital, Alicante, Spain. acien@umh.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology Adult Age Factors Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols / therapeutic use Carboplatin / administration & dosage Carcinoma, Squamous Cell / etiology, mortality, pathology*, therapy Chemotherapy, Adjuvant / methods Cisplatin / administration & dosage Endometriosis / complications*, pathology Female Humans Middle Aged Neoplasm Staging Neoplasms, Multiple Primary Ovarian Neoplasms / etiology, mortality, pathology*, therapy Paclitaxel / administration & dosage Prognosis Uterine Cervical Neoplasms / pathology |
| Chemical | |
Reg. No./Substance:
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15663-27-1/Cisplatin; 33069-62-4/Paclitaxel; 41575-94-4/Carboplatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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