Document Detail


Primary squamous cell carcinoma of the ovary associated with endometriosis.
MedLine Citation:
PMID:  19782981     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the clinical, therapeutic, and pathologic features of published cases presenting primary squamous cell carcinoma (SCC) of the ovary associated with endometriosis. METHODS: A case report, 15 cases of infiltrating SCC of the ovary associated with or arising from endometriosis, and 1 case of synchronous carcinoma in situ in the cervix and ovary from a review of the literature were studied. RESULTS: Young age, advanced stage of the disease, and hypogastric pain were frequent at the time of diagnosis. There was no ascites, but infiltration of neighboring organs was common. The tumor was associated with 80% patient mortality in the first few months. Adjuvant chemotherapy with paclitaxel and carboplatin or cisplatin appeared to improve the results. CONCLUSION: Primary SCC of the ovary associated with endometriosis is extremely rare and has a poor prognosis. The best therapeutic results are obtained with paclitaxel and carboplatin or cisplatin after radical surgery.
Authors:
Pedro Aci?n; Maida Abad; Maria-Jos? Mayol; Salvador Garcia; Javier Garde
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  108     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  16-20     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, San Juan University Hospital, Alicante, Spain. acien@umh.es
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MeSH Terms
Descriptor/Qualifier:
Abdominal Pain / etiology
Adult
Age Factors
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Carboplatin / administration & dosage
Carcinoma, Squamous Cell / etiology,  mortality,  pathology*,  therapy
Chemotherapy, Adjuvant / methods
Cisplatin / administration & dosage
Endometriosis / complications*,  pathology
Female
Humans
Middle Aged
Neoplasm Staging
Neoplasms, Multiple Primary
Ovarian Neoplasms / etiology,  mortality,  pathology*,  therapy
Paclitaxel / administration & dosage
Prognosis
Uterine Cervical Neoplasms / pathology
Chemical
Reg. No./Substance:
15663-27-1/Cisplatin; 33069-62-4/Paclitaxel; 41575-94-4/Carboplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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