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Primary squamous cell carcinoma of the liver: A case report and review of the literature.
MedLine Citation:
PMID:  23197996     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Primary squamous cell carcinoma of the liver is rare. It has a high malignancy rate and poor prognosis, and survival is typically no longer than one year. The pathogenesis of the disease is unclear, but is generally considered to be correlated with the long-term inflammation or metaplasia of biliary epithelial cells and congenital cyst of the liver. The current viewpoint is that surgical resection of the tumor, preoperative or postoperative subsidiary chemoembolization, radiotherapy and generalized chemotherapy may extend a patient's survival. In the present case study, a patient suffered from biliary calculosis for over 20 years. We theorized that the mechanism of carcinomatous change was correlated with the persistent stimulation of chronic biliary infection induced by calculus of the intrahepatic duct. However, the transformation mechanism from cholangiocellular carcinoma to squamous carcinoma is undetermined and further studies are needed.
Authors:
Rongrong Zhao; Kunli Zhu; Renben Wang; Jie Gao; Kai Cui; Fachang Yu; Bo Zhang; Sheng Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-05
Journal Detail:
Title:  Oncology letters     Volume:  4     ISSN:  1792-1082     ISO Abbreviation:  Oncol Lett     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101531236     Medline TA:  Oncol Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1163-1166     Citation Subset:  -    
Affiliation:
Department of Hepatobiliary Surgery, Shandong Cancer Hospital, Jinan 276000;
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