Document Detail

Primary small cell carcinoma of lacrimal sac: case report and literature review.
MedLine Citation:
PMID:  20412615     Owner:  NLM     Status:  In-Process    
OBJECTIVE: We present the first reported case of primary small cell carcinoma of the lacrimal sac.
CASE REPORT: A 67-year-old Japanese woman was referred to our department with a two-month history of left medial canthal swelling, epiphora and occasional nasal bleeding. Nasal endoscopy revealed a readily bleeding tumour in the left inferior meatus. Computed tomography and magnetic resonance imaging scans demonstrated that the tumour was mainly located in the left lacrimal sac. Histopathological studies of a biopsy specimen revealed small cell carcinoma. The patient was treated with four cycles of chemotherapy consisting of cisplatin and etoposide, in combination with radiotherapy. There was no evidence of recurrence or metastasis for five years.
CONCLUSION: Small cell carcinoma originating in the head and neck region has been reported to be highly aggressive and to have a poor prognosis. We report a case of primary small cell carcinoma of the lacrimal sac successfully treated with chemo-radiotherapy.
T Goto; N Bandoh; T Nagato; M Takahara; Y Harabuchi; Y Tokusashi; N Miyokawa
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Publication Detail:
Type:  Journal Article     Date:  2010-04-23
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  124     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1223-6     Citation Subset:  AIM; IM    
Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical College, Obihiro, Japan.
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