| Primary signet-ring cell carcinoma mimicking segmental Crohn's colitis. | |
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MedLine Citation:
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PMID: 15975543 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary signet-ring cell carcinoma of the colon is a rare entity with a dismal prognosis, mainly due to a delay in diagnosis. Here, we present a case of a 30-year-old Filipino woman who presented with symptoms mimicking inflammatory bowel disease. A barium enema and colonoscopy demonstrated a stricture in the rectosigmoid region. A biopsy revealed granulomatous changes indicative of inflammatory bowel disease. Despite initial improvement of her symptoms on total parenteral nutrition and steroids, the patient relapsed several weeks later with recurrent left lower quadrant pain. A subsequent biopsy revealed poorly differentiated signet-ring cell carcinoma of the colon. She was treated surgically with a left hemi-colectomy and primary repair. A high degree of suspicion is necessary to correctly diagnose these, often young, patients with primary signet-ring cell carcinoma early and have a positive impact on survival. The literature on primary signet-ring cell carcinoma is reviewed. |
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Authors:
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H E Achneck; S K Pradhan; S M Kavic; W E Longo |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2005-04-08 |
Journal Detail:
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Title: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Volume: 37 ISSN: 1590-8658 ISO Abbreviation: Dig Liver Dis Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-06-24 Completed Date: 2005-10-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100958385 Medline TA: Dig Liver Dis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 537-41 Citation Subset: IM |
Affiliation:
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Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology Adult Barium Sulfate / diagnostic use Carcinoma, Signet Ring Cell / complications, diagnosis*, surgery Colectomy Colonic Neoplasms / complications, diagnosis*, surgery Colonoscopy Crohn Disease / diagnosis*, surgery Enema Female Humans Recurrence |
| Chemical | |
Reg. No./Substance:
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7727-43-7/Barium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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