Document Detail

Primary signet-ring cell adenocarcinoma of the endometrium: case report and review of the literature.
MedLine Citation:
PMID:  20407328     Owner:  NLM     Status:  MEDLINE    
Endometrial adenocarcinoma presenting with deep venous thrombosis is an exceptional event more typical of extra-mullerian primary tumors. Metastases to the spleen are also unusual in this setting. In addition, primary endometrial adenocarcinoma with signet-ring cell features has been reported only once. This study describes a case of primary endometrial carcinoma with prominent signet-ring cell features that presented in an unusual manner: with bilateral deep vein thromboses and splenic metastases. It is important for clinicians and pathologists to be aware of this entity; it may have an atypical clinical presentation and the histologic features raise a spectrum of differential diagnoses.
Ivan Chebib; Pamela Chu; Maire A Duggan; Lisa M DiFrancesco
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists     Volume:  29     ISSN:  1538-7151     ISO Abbreviation:  Int. J. Gynecol. Pathol.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-07-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214845     Medline TA:  Int J Gynecol Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  269-72     Citation Subset:  IM    
Department of Pathology and Laboratory Medicine, University of Calgary, and Calgary Laboratory Services, 11th Floor, Foothills Medical Center, 1403-29 Street NW, Calgary, Alberta, Canada T2N 2T9.
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MeSH Terms
Carcinoma, Signet Ring Cell / blood,  pathology*,  secondary,  surgery
Endometrial Neoplasms / blood,  pathology*,  surgery
Fatal Outcome
Splenic Neoplasms / blood,  secondary*,  surgery
Venous Thrombosis / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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