Document Detail

Primary and secondary results of the modification of diet in renal disease study.
MedLine Citation:
PMID:  8676806     Owner:  NLM     Status:  MEDLINE    
The modification of diet in renal disease (MDRD) study was a prospective, randomized, multicenter trial in 840 patients with chronic renal disease of diverse etiology. Patients in study A (585) had a GFR of 25-55 ml/min at baseline and patients in study B (255) had a GFR of 13-24 ml/min. After randomization to different diet and blood pressure groups the mean follow-up was 2.2 years. The results of the blood pressure and dietary interventions on GFR decline with time are summarized.
S Klahr
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  Mineral and electrolyte metabolism     Volume:  22     ISSN:  0378-0392     ISO Abbreviation:  Miner Electrolyte Metab     Publication Date:  1996  
Date Detail:
Created Date:  1996-08-12     Completed Date:  1996-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802196     Medline TA:  Miner Electrolyte Metab     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  138-42     Citation Subset:  IM    
Department of Medicine, Washington University School of Medicine at The Jewish Hospital of St. Louis, Mo 63110, USA.
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MeSH Terms
Amino Acids
Antihypertensive Agents / therapeutic use*
Blood Pressure*
Diet, Protein-Restricted*
Follow-Up Studies
Food, Fortified
Glomerular Filtration Rate
Kidney Diseases / diet therapy*,  physiopathology*
Middle Aged
Nutrition Disorders
Prospective Studies
Serum Albumin / analysis
Time Factors
Transferrin / analysis
Reg. No./Substance:
0/Amino Acids; 0/Antihypertensive Agents; 0/Serum Albumin; 11096-37-0/Transferrin

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