Document Detail


Primary progressive aphasia: a case report.
MedLine Citation:
PMID:  10362910     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 69-year-old male patient whose motor aphasia started at the age of 61. The language disability remained isolated and progressed over a period of eight years without any additional cognitive deficits. Computed tomography (CT) and magnetic resonance imaging (MRI) showed moderate cortical atrophy with frontal dominance. Single photon emission tomography (SPECT) showed hypoperfusion in the frontotemporoparietal region, positron emission tomography (PET) demonstrated a global cortical reduction of glucose utilization with a lesser decrement in the occipital lobes. The clinical symptoms and the neuropsychological findings fit the diagnosis of primary progressive aphasia.
Authors:
T G Nagy; I Jelencsik; I Szirmai
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of neurology : the official journal of the European Federation of Neurological Societies     Volume:  6     ISSN:  1351-5101     ISO Abbreviation:  Eur. J. Neurol.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  2000-06-21     Completed Date:  2000-06-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9506311     Medline TA:  Eur J Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  515-9     Citation Subset:  IM    
Copyright Information:
Copyright 1999 Lippincott Williams & Wilkins
Affiliation:
Department of Neurology, Semmelweis Medical University, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aphasia, Primary Progressive / pathology,  physiopathology*,  psychology
Atrophy
Brain / pathology
Cerebrovascular Circulation
Disease Progression
Humans
Magnetic Resonance Imaging
Male
Neuropsychological Tests
Speech
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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